Fire Fighters in Painful Sex Emergency – Man Gets Erect Penis Jammed in 13 Cock Rings

Fire Fighters in Painful Sex Emergency – Man Gets Erect Penis Jammed in 13 Cock Rings: Yesterday the German fire brigade was asked by a local hospital to use their precision grinding equipment to remove 13 penis rings from a 52 year old man – more details with link to video below.

German Firefighters - Ready For The Next Emergency
German Fire-fighters – Ready For The Next Erectile Dysfunction Emergency

Yesterday (Tuesday 8th March 2016) at 13:15 a hospital in Germany had to call in the local fire fighters with their specialised technology and expertise to help with a particularly sensitive problem faced by a 52 year old man – or to be more precise his penis.

While you read why not listen to my album ‘Electro Baroque‘ (all tracks are also available on iTunes using the link here)? Classical music using modern instruments:

or if you prefer to listen to my electro/techno album ‘Studio Valiumm‘ here are the videos (also on iTunes using the link here):

More info about my music is at the dedicated website www.TRANSFORMATES.com

Let me fist provide you with some medical context. Sometimes when men suffer with erectile dysfunction they may consider using an implement known as a penis or cock ring. Erectile dysfunction refers to the inability of one’s penis to inflate with blood and stay inflated – it is a complaint that mainly affects men. By applying the ring to a gentleman’s appendage it is possible to reduce the flow of blood out of the appendage and thus maintain an erect state longer than might otherwise be possible.

A made-to-measure 55 mm Metal Penis Ring of the type sometimes used for erectile dysfunction
A made-to-measure 55 mm Metal Penis Ring of the type sometimes used for erectile dysfunction

A person with erectile dysfunction, perhaps due to a nerve or vascular damage, may be able to use a special vacuum pump attached to the end of his penis to create an erection. A ring then slips off the pump onto the base of the penis to help maintain the erectile state so that the person can participate in sexual intercourse.

Sometimes these rings are used by people who do not have this medical problem and it is suspected that the man in the German hospital accident and emergency department wearing 13 penis rings may fall into this category. It appears that he had already been wearing his penis rings for four days – the pain had become so unbearable that he decided he needed medical assistance. The hospital could not remove the rings. This is where the fire fighting professionals with their specialised grinding equipment were able to help.

Standard Angle Grinder used by emergency services - for penis rings a smaller device tends to be preferable
Standard Angle Grinder of the type used by emergency services – for penis rings a smaller device tends to be more appropriate (see video from NDR below)

As with any medical device there can be risks associated with the use of a cock ring. Generally the suppliers of these implements, as well as knowledgeable medical sources, indicate they should not be worn for more than 30 minutes. In particular care should be taken not to fall asleep while wearing the device – this can lead to temporary or permanent nerve damage. Illicit drug taking with the device is also dangerous. Penis rings should be removed at the first sign of problems (e.g. penile numbness, coldness or paleness).

If worn for too long the ring can lead to priapism in which the penis does not return to its flaccid (‘non-inflated’) state within an appropriate amount of time. This is a medical emergency situation and can lead to permanent damage including, in severe cases, gangrene. Gangrene can destroy the penis and may require for it to be amputated.

Example of Gangrene (please note this is a foot not a penis)
Example of Gangrene (please note this is a foot not a penis)

Fortunately the German fire fighters were able to remove the man’s 13 penis rings using their specialised equipment and training. Apparently cock ring removal is not an infrequent occurrence but it is very rare to have to deal with 13 rings all on the same appendage. Following their removal the medical staff at the hospital were able to administer further treatment to the patient.

I did a check to find out how these emergency fire fighters train for these sensitive incidents. Clearly it is rather difficult to train on live people for risk of any accidental slippage of the grinding equipment. To address this German teams have come up with a solution which I suspect could only have been devised in the land that claims to have invented the sausage. If you would like to see the team from the Osnabrück fire brigade during their Penis Ring Removal Training Exercise take a look at the report from NDR below (if you can’t read the German just click on the video – it is pretty self explanatory):

LINK to Cock Ring Removal Video: Feuerwehr in Osnabrück übt Penisring-Einsatz

Here in South Africa we have our own way of helping people who may be struggling with sexually related problems. If you know of someone in this situation please do not hesitate to share with them my video of the local Tribal Fertility Dance – but be warned – ladies should only listen to this music in a suitably private location. I do not accept any liability for the effect this video will have on their desire for passionate satisfaction.

I hope you found this article useful and perhaps educational. If you do use penis rings please take care to follow the supplier’s instructions and as always, if in doubt, seek professional medical advice. If you do get stuck – Germany’s not a bad place to get stuck in.

Chris Duggleby

German Firefighters - Primed and ready for the next penis ring emergency
German Fire Fighters – Primed and ready for the next penis ring emergency

If you found this article interesting please consider taking a look at some of his other recent reports on similar subjects.

Just click on the titles below:

here are some more fun reports…

28th Feb 2017: Vaccinations Cause Children to Masturbate, as well as Dyslexia, Autism, Sleep Disorders and Brain Tumours

4th Mar 2016: Dachau Industry Park Evolves From Concentration Camp To Nudist Wellness Club (Brothel)

21st June 2015: Bio-undies: Guilt free Passion with ‘Easy Emma’ and ‘Loose Harry’and Getting Rid of Garden Snails with Rent-a-Duck

4th March 2015: Hamburg Reeperbahn (St. Pauli): Germans install walls that urinate on passers-by

17th April 2014: Niche On-line Dating Services (Specialities: Herpes, Thrush and Genital Warts)

18th March 2014: Germany and Finland Joint Investigation: New Case of Sexual Cannibalism Including Self-mutilation (Castration) During Intercourse.

18th August 2012: How Bavarians and Austrians use their middle finger – Fingerhakeln: a men-only sport (did Arnold Schwarzenegger start training this way?).

You can also find even more of my humorous reports in the Alpine Press section of this site using the link here.

…and for those who like more serious stuff…

3rd March 2016 Using Gene Drives To Change Mosquito Sex In Fight Against Zika, Dengue and Malaria 

1st March 2016 Ladies – upto half a satisfying sexual event per month but risk of side effects from “Pink Viagra” Flibanserin (“Addyi”)

14th Feb 2016 Breast Cancer – How Blind People Use Their Enhanced Tactile Sensitivity to Save the Lives Of Women With Tumours

3rd Feb 2016 Zika Infection Spread By Sex In Dallas – Earlier Sexual Transmission In Colorado – Detailed Symptoms 

1st Feb 2016 Sexual Competition Between Women – Ovulation Can Be Seen In The Face

31st Jan 2016  Bed Bugs – Insecticide Resistance – Arbovirus Transmission – Zika and Microcephy

19th Jan 2016 ZIKA Virus Epidemic  – Health Warning – Pregnant women should postpone travel to affected areas – Including Brazil 

17th Jan 2016 Bubonic Plague Special – LiceHosts for The Black Death Bug

13th Jan 2016 Kill Head Lice In A Day With The Newly Developed Plasma Nitcomb From The German Fraunhofer Institute

8th Jan 2016 Cancer from Handbags, Shoes and Gloves – Allergic Reactions to Jewellery – German Institute Identifies Excessive Chromium 6 and Nickel Levels

26th July 2015 Poison in your Washing Machine: Allergic Contact Dermatitis from Laundry Detergents, Softeners, Conditioners and Whiteners

17th October 2015: Health Risk: Vitamin and antioxidant supplements help cancer cells become malignant – latest research from Texas

31st May 2015: German Concern about Potentially Carcinogenic Aromatic Hydrocarbons in Cosmetics  

29th December 2012: Spreading diarrhea and vomit through the washing machine – The Norovirus propagator in our kitchen

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The Gene Drive Dilemma – Save Lives From Zika Malaria and Dengue – Downside Unknown

The Gene Drive Dilemma – Save Lives From Zika Malaria and Dengue – Downside Unknown – We are at a serious evolutionary cross-roads because powerful Molecular Biology tools like CRISPR/Cas9 Gene Editing techniques have opened the door to the creation of Gene Drives. These introduce and proliferate new or altered genes in nature. The technology might provide a way of saving millions of lives (e.g. from malaria) but there are serious concerns about the potential downsides.

Ethiopian Child With Malaria - 438,000 were killed in 2015 by this killer disease - mainly in Africa, mostly children (W.H.O.)
Ethiopian Child With Malaria – 438,000 were killed in 2015 by this killer disease – mainly in Africa, mostly children (W.H.O.)

On Feb 17th 2016 researchers Zach Adelman and Zhijian Tu published their discovery of Nix, a sex gene in Aedes aegypti mosquitoes. These are the mosquitoes that transmit virus diseases to humans like Zika, Dengue Fever, Yellow Fever and Chikungunya. Their findings may also be applicable to the Anopheles mosquito that transmits malaria – a disease which killed 438,000 people in 2015 with 214 million new cases reported – mainly in Africa (figures from the World Health Organisation’s 2015 Malaria report).

While you read why not listen to my album ‘Electro Baroque‘ (all tracks are also available on iTunes using the link here)? Classical music using modern instruments:

or if you prefer to listen to my electro/techno album ‘Studio Valiumm‘ here are the videos (also on iTunes using the link here):

More info about my music is at the dedicated website www.TRANSFORMATES.com

What is the Nix Sex Gene?

As demonstrated in the research paper by Messrs Adelman and Tu it is possible to perform gender conversion for the Aedes aegypti mosquito. Their work identified the Nix ‘sex gene’ which produces a protein very early in the development of the mosquito to programme its development as a male. The mosquito develops as a female if this gene is not sufficiently expressed (in other words the sex protein that it generates is either not produced or produced incorrectly). To demonstrate the existence and influence of Nix on mosquitoes the researchers used the latest highly specific gene manipulation technology called CRISPR-Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats associated with the DNA cutting enzyme Cas9). This is a process that evolved in bacteria as an immune system to defend them against bacterial viruses – it can be used for very precise editing of chromosomes.

The Role of the Nix Gene in Aedes aegypti mosquitoes Copyright 2016 Chris DugglebyUsing CRISPR-Cas9 to knock-out the Nix gene, genetically ‘male’ mosquitoes could be feminized and developed female genitals and antenna (which are not found on males). The converse occurred in genetically ‘female’ mosquitoes into which the Nix gene was ‘injected’ and made to produce it’s protein. These female mosquitoes developed both external and internal male genitalia (testes and associated male sex glands). Thus the Nix sex gene was used to successfully ‘gender reassign‘ these Aedes aegypti mosquitoes.

Why is mosquito sex important when trying to combat killer diseases?

One of the most effective ways of combating killer diseases spread by mosquitoes is to reduce the population of the insects involved (e.g. Anopheles mosquitoes for malaria and Aedes aegypti mosquitoes for Dengue, Yellow Fever, and Zika). The use of insecticides is becoming less effective due to increasing mosquito resistance. Physical approaches like eliminating the sources of standing water that provide the mosquitoes with breeding grounds need to be very thorough and strictly implemented to have a significant effect.

Spraying kerosene oil in 1912 - a less effective approach to dealing with the global malaria problem.
Spraying kerosene oil in 1912 – a less effective approach to dealing with the global malaria problem.

It is the female mosquito that feeds on human blood and is therefore responsible for transmitting the diseases mentioned above. The male of the species does not feed on human blood, preferring to derive its nutrition from nectar. Because of this scientists are particularly interested to find ways of reducing the number of female rather than male mosquitoes.

Some authorities are experimenting with releasing sterile male mosquitoes into the wild. These compete against normal ‘wild’ male mosquitoes to mate with females. Since the female only copulates once in her lifetime the number of offspring can be reduced if sufficient sterile male mosquitoes are released. To make them sterile the male mosquitoes either have their genes modified by radiation or they may contain a ‘killer’ gene which prevents them from producing fertile offspring. Some problems with this approach are:

  • Only males should be released (any females in the release batch would increase the number of disease carriers and therefore must be identified and destroyed)
  • The sterile males have to be released in large enough numbers to have an impact when competing with the fertile males that already exist in the wild
  • The release must be part of a continuous programme – any reduction in the numbers released would allow the remaining native fertile males to mate, multiply and produce more females.

    The Aedes aegypti mosquito - vector of Zika, Dengue Fever, Yellow Fever and Chikungunya
    The Aedes aegypti mosquito – vector of Zika, Dengue Fever, Yellow Fever and Chikungunya

The advantage of this sterile male approach over the use of chemical and biological insecticides (like bacteria that kill mosquitoes) is that it can get more effectively to areas with lower concentrations of mosquitoes – the released males are pretty keen on finding a partner to mate with – the fewer the number of ladies – the harder they look!

Gene manipulation approaches such as those based on the use of the Nix sex gene could be designed to address the issue of removing females from the release batch (all mosquitoes are ‘converted’ to males – thereby doubling the number of potential ‘male’ partners in the batch). The approach can be further developed to ensure that copulation with a released male will only produce more males (no female offspring). Alternatively it might be possible to ensure that any female offspring die (using a ‘lethal when female‘ gene combination). These developments involve what is termed a Gene Drive.

What is a Gene Drive?

The purpose of a Sex Gene Drive is to increase (‘drive-up’) the ratio of non-blood sucking males in the mosquito population. The term gene drive is used when a genetic attribute (like maleness) in a population is increased (or decreased) compared with the natural levels expected (e.g. for maleness the target is to have more then the usual 50% male offspring). A gene drive is inherited from generation to generation so for each mating cycle the relevant gene (e.g. Nix) continues to have its effect (increases the number of males) until eventually all offspring have the gene and there are no females left. If successful this mosquito species disappears.

How does a Gene Drive Work A see Sex Gene Drives in Mosquitoes by Chris DugglebyHow does a Gene Drive Work B see Sex Gene Drives in Mosquitoes by Chris DugglebyThe advantage of using gene drive approaches is that a smaller number of mosquitoes need to be released because the new attribute (e.g. to be male) is self sustaining and increases in the population from generation to generation. As well as trying to influence the proportion of males in the mosquito population (as with ‘driving up’ the Nix gene) other genes could be used in gene drives such as those which make the mosquitoes resistant to being infected by the specific parasite or virus that causes harm to humans (e.g. the malaria parasite or Zika virus). Researchers are also trying to develop gene drives which reduce the ability of female mosquitoes to have offspring.

A gene drive to create males of the Anopheles gambiae mosquito (which transmits malaria in Africa) is close to being field tested by Austin Burt and colleagues in Africa. These mosquitoes are like humans in that their sex is determined by the possession of X and Y chromosomes (XX = female, XY = male). Normally half the mosquito sperm would have a Y chromosome and half would contain an X. All the eggs produced by the female have a X chromosome so upon mating you would then have a population of half XX (female) and half XY (male). The altered mosquitoes with the gene drive only produce sperm containing a Y sex chromosome.How a Male Sex Gene Drive Works Copyright 2016 Chris Duggleby

Using a meganuclease based gene drive system Burt and his team have produced Malaria transmitting mosquitoes in which all the males only produce sperm with an Y chromosome and any females mating with these mosquitoes will only produce males. This trait is then ‘driven’ into the next generation so that any wild females mating with these ‘altered’ male offspring also only produce males. Eventually this would destroy the population due to lack of any remaining females (this project is funded by the Gates Foundation).

Among the gene drives being developed using the CRISPR/Cas9 techology one also reduces female mosquito fertility and in another case the mosquito is given a gene to make it resistant to the parasite that causes malaria (protozoa belonging to the Plasmodium family). This is in addition to a potential drive incorporating the Nix male sex determining gene to drive an increase in populations of wild Aedes aegypti (Dengue, Zika, Chikungunya, Yellow Fever) and Anopheles gambiae (Malaria) mosquitoes.CRISPR Associated Protein see Sex Gene Drives in Mosquitoes by Chris Duggleby

Ethical Considerations

Gene manipulation of species released into the wild is a very controversial subject. The debate about genetically modified crops has received considerable press and political attention. Crops can’t fly on their own! The idea of releasing genetically modified mosquitoes into the wild will certainly need to be thoroughly researched and given very careful consideration. The scientific community is clearly not ready for such a step today but it will be within the next 5-10 years. The speed of developing and testing gene drives is dependant on the life cycle of the species involved – the mosquito life cycle is very short so a system can be tested in a couple of years (a human gene drive would require decades or centuries to fully field test because we are much older before we reproduce).

One of the particularly worrying things about using gene drive technology is that it does not just change the current generation but the technology alters all the offspring for generations to come. Once released into the wild it will be impossible to stop working in the offspring that inherit the new genes. We would be altering the make up of the natural gene pool over time. Some processes are being designed which could neutralise the impact for example by using another gene drive to ‘re-inject’ and drive back up the levels of a ‘corrected’ gene in the population. However, these systems would not remove any of the changes to organisms in the wild that have already been created by an earlier ‘rogue’ gene drive. The neutralizing systems would be aimed at diluting the impact of these changes on the ecosystem by adding large numbers of ‘corrected’ organisms.

Those in favour of using such new technologies will want to take advantage of their potential to save lives (like the nearly half a million lives lost to malaria each year – mainly young children). Human activities have helped these mosquitoes to enter into new regions of the World and some will argue that eliminating the insects from these new areas will simply be reinstating the natural state. One of the reason Zika has been so successful in spreading throughout the American continent is that it is a new disease here and the local population has not previously been exposed to the virus. There is therefore no natural immunity (much like the small pox, influenza and measles that Europeans introduced into the Americas, Australia and Africa killing huge numbers of the indigenous populations on those continents).

Fortunately the responsible members of the scientific community are very wary of proceding with field trials of these new techniques until the ethical and regulatory issues have been thoroughly discussed and a consensus with both authorities and the general public is reached on the most appropriate way forward. However these tools are so powerful that it may only take an accidental release of an ‘engineered’ organism into the wild to have a potentially devastating impact on the genetic composition of the native species.

Of particular concern is the potential use of this technology by a rogue state or terrorist organisation for the purposes of biological warfare or to simply terrorise those of opposing beliefs. One of the characteristics of the CRISPR/Cas9 system is that is is relatively easy to design and use compared with previous genetic engineering systems. Laboratories with basic skills in modern molecular biology and genetic engineering could (and are) developing these organisms.

My personal fear is that we could be releasing into nature a powerful self replicating system – if we can add passenger genes to gene drive systems surely it is conceivable that other genes could try and hitch a lift. For example cancer genes – those involved with cancer biology will be well aware of how some viruses have managed to insert human type oncogenes (cancer causing genes) into their genome (For techies: I am thinking here of the postulation that a non-carcinogenic evolutionary predecessor of the Rous Sarcoma Virus incorporated the src oncogene into its genome – converting it into the cancer causing agent of today). It would be a cruel outcome if a genetic device that we introduce into nature to save millions of lives is able, through mutation or genetic recombination, to itself become a powerful pathogen. Clearly we need to ensure any safeguards are foolproof and novel systems are thoroughly tested.

We have reached a very serious junction in which humanity could either wisely develop systems to eradicate painful and deadly diseases or destroy the balanced ecosystem upon which we depend. Watch this space!

Chris Duggleby  

Female Mosquito Feeding (Anopheles stephensi)
Female Mosquito Feeding (Anopheles stephensi)

If you found this article interesting please consider taking a look at some of his other recent reports on similar subjects.

Just click on the titles below:

…starting with some more serious stuff…

28th Feb 2017: Vaccinations Cause Children to Masturbate, as well as Dyslexia, Autism, Sleep Disorders and Brain Tumours

1st March 2016 Ladies – upto half a satisfying sexual event per month but risk of side effects from “Pink Viagra” Flibanserin (“Addyi”)

14th Feb 2016 Breast CancerHow Blind People Use Their Enhanced Tactile Sensitivity to Save the Lives Of Women With Tumours

3rd Feb 2016 Zika Infection Spread By Sex In Dallas – Earlier Sexual Transmission In Colorado – Detailed Symptoms 

1st Feb 2016 Sexual Competition Between Women – Ovulation Can Be Seen In The Face

31st Jan 2016  Bed Bugs – Insecticide Resistance – Arbovirus Transmission – Zika and Microcephy

19th Jan 2016 ZIKA Virus Epidemic  – Health Warning – Pregnant women should postpone travel to affected areas – Including Brazil 

17th Jan 2016 Bubonic Plague Special – Lice – Hosts for The Black Death Bug

13th Jan 2016 Kill Head Lice In A Day With The Newly Developed Plasma Nitcomb From The German Fraunhofer Institute

8th Jan 2016 Cancer from Handbags, Shoes and Gloves – Allergic Reactions to Jewellery – German Institute Identifies Excessive Chromium 6 and Nickel Levels

26th July 2015 Poison in your Washing Machine: Allergic Contact Dermatitis from Laundry Detergents, Softeners, Conditioners and Whiteners

17th October 2015: Health Risk: Vitamin and antioxidant supplements help cancer cells become malignant – latest research from Texas

31st May 2015: German Concern about Potentially Carcinogenic Aromatic Hydrocarbons in Cosmetics  

29th December 2012: Spreading diarrhea and vomit through the washing machine– The Norovirus propagator in our kitchen

and here are some fun reports…

21st June 2015: Bio-undies: Guilt free Passion with ‘Easy Emma’ and ‘Loose Harry’and Getting Rid of Garden Snails with Rent-a-Duck

4th March 2015: Hamburg Reeperbahn (St. Pauli): Germans install walls that urinate on passers-by

17th April 2014: Niche On-line Dating Services (Specialities: Herpes, Thrush and Genital Warts)

18th March 2014: Germany and Finland Joint Investigation: New Case of Sexual Cannibalism Including Self-mutilation (Castration) During Intercourse.

18th August 2012: How Bavarians and Austrians use their middle finger – Fingerhakeln: a men-only sport (did Arnold Schwarzenegger start training this way?).

You can also find some of my more humorous reports in the Alpine Press section of this site using the link here.

Pink Viagra – Extra Half Orgasm Per Month But It Could Make You Dizzy And Throw Up

Pink Viagra – Extra Half Orgasm Per Month But It Could Make You Dizzy And Throw Up A research review of Flibanserin (trade name Addyi) was published in the JAMA Internal Medicine journal on 29th February 2016. This is used to treat Hypoactive Sexual Desire in Women (the lack or absence of sexual fantasies and a lack of desire for sexual activity). The improvement in Satisfying Sexual Events (SEEs) was quantified (see below) as were some of the side effects.

Model of Flibanserin
Model of Flibanserin

The developers of the “female libido pill” Flibanserin (marketed under the name Addyi) have clearly demonstrated commitment to their product having had it rejected twice by the US Food and Drug Administration (FDA). Flibanserin started life as an antidepressant but following its failure in that application found a new lease of life as a potential treatment for hypoactive sexual desire disorder (HSDD) in pre-menopausal women. This is defined as a sexual dysfunction characterized as a lack or absence of sexual fantasies and a lack of desire for sexual activity (as judged by a medical professional).

While you read why not listen to my album ‘Electro Baroque‘ (all tracks are also available on iTunes using the link here)? Classical music using modern instruments:

or if you prefer to listen to my electro/techno album ‘Studio Valiumm‘ here are the videos (also on iTunes using the link here):

More info about my music is at the dedicated website www.TRANSFORMATES.com

In the FDA’s first evaluation of this drug for improving sexual desire in women (2009) the clinical reviewers and an external advisory committee voted unanimously (11-0) against approving Flibanserin. They concluded that its uncertain benefit did not outweigh its harms. In 2013, after Sprout Pharmaceuticals had acquired the rights to the drug, it was resubmitted to the FDA with a new efficacy (ability to produce the desired effect) trial and interaction studies. For this submission the drug’s interaction with alcohol was tested – interestingly on men rather than the target population of pre-menopausal women. The combination of the two drugs led to an increase in hypo-tension (low blood pressure). Other tests, this time with women, in combination with certain medications (fluconazole, a CYP3A4 inhibitor used to treat candida in ‘Yeast infections‘) also led to hypo-tension. The FDA rejected flibanserin a second time concluding that the small treatment differences (sexual desire benefits) did not clearly outweigh safety concerns. An appeal by Sprout was unsuccessful.

Model of Fluconazole used to treat Yeast Infections
Model of Fluconazole used to treat Yeast Infections

Prior to its third submission to the FDA Sprout supported the launch of an advocacy group ‘Even The Score‘ which conducted an intense promotional campaign towards journalists, women’s groups, congress and the FDA. The advocacy group campaign emphasized that although there were several approved treatments for male sexual dysfunction, no such treatment for women was then available. From their website: “Even the Score: A campaign for women’s sexual health equity was created to serve as a voice for American women who believe that it’s time to level the playing field when it comes to the treatment of women’s sexual dysfunction” – link here.

The third submission to the FDA occurred in 2015 and although it did not include new information about the efficacy of the drug it did have some reassuring information about the potential of the drug to cause somnolence (sleepiness or drowsiness) when driving. Unfortunately other information submitted did heighten concerns relating to dangerous interactions with other drugs.

With regard to this submission there was some dissent within the FDA. Its own clinical reviewers still recommended rejection: “We do not believe that it is reasonable for the approximately 90% of treated patients who will not respond to the product to be exposed to the numerous serious risks posed by flibanserin therapy.” They were overruled by two FDA directors who, while acknowledging the limited efficacy and worrisome harms of the drug, emphasized that it met a need in women for whom other (sexual desire) treatments had failed. The drug was approved but the FDA required that it has a black box label, their most serious safety alert, reflecting problems associated with the drug. Clearly the advocacy group’s message had reached its target.

Upon getting FDA approval flibanserin was sold to Valeant Pharmaceuticals for around $1 billion.

The new report in the JAMA Internal Medicine journal involved a systematic review and meta analysis of 8 previous studies into the efficacy and safety of flibanserin for the treatment of Hypo Sexual Desire Disorder. Nearly 6000 women were involved. The treatment resulted on average in one half of a satisfying sexual experience per woman per month compared with placebos (non-effective pills without any active ingredient). Against this benefit a significant increased risk of dizziness, somnolence, nausea and fatigue was identified. The authors of the paper (Jaspers et al) concluded that the modest sexual desire benefits of the drug did not outweigh its harms. In addition to the negative effects mentioned above was the risk of hypo-tension and syncope (fainting/passing out caused by reduced flow of blood to the brain) when combining flibanserin with alcohol and some other common drugs.

The authors recommended more research including women from diverse populations e.g. those with co-morbidities (additional disorders or diseases), those using other medication and those having undergone surgical menopause. The original papers reporting this work can be found using the links here and here.

If in doubt always check with your medical doctor.

Chris Duggleby

Hypoactive Sexual Desire? Why not try my African Tribal Fertility Dance? According to the Pretty Spandex Boys it can improve the sexual desire of both genders:

Black Pudding Breakfast - a Scottish approach to dealing with sexual dysfunction - sometimes known as the "morning after pill". Apparently it works on both sexes.
Black Pudding Breakfast – a Scottish approach to dealing with sexual dysfunction – sometimes known as the “morning after pill”. Apparently it also works on both sexes.

If you found this article interesting please consider taking a look at some of his other recent reports on similar subjects.

Just click on the titles below:

…starting with some more serious stuff…

28th Feb 2017: Vaccinations Cause Children to Masturbate, as well as Dyslexia, Autism, Sleep Disorders and Brain Tumours

14th Feb 2016 Breast CancerHow Blind People Use Their Enhanced Tactile Sensitivity to Save the Lives Of Women With Tumours

3rd Feb 2016 Zika Infection Spread By Sex In Dallas – Earlier Sexual Transmission In Colorado – Detailed Symptoms 

1st Feb 2016 Sexual Competition Between Women – Ovulation Can Be Seen In The Face

31st Jan 2016  Bed Bugs – Insecticide Resistance – Arbovirus Transmission – Zika and Microcephy

19th Jan 2016 ZIKA Virus Epidemic  – Health Warning – Pregnant women should postpone travel to affected areas – Including Brazil 

17th Jan 2016 Bubonic Plague Special – Lice – Hosts for The Black Death Bug

13th Jan 2016 Kill Head Lice In A Day With The Newly Developed Plasma Nitcomb From The German Fraunhofer Institute

8th Jan 2016 Cancer from Handbags, Shoes and Gloves – Allergic Reactions to Jewellery – German Institute Identifies Excessive Chromium 6 and Nickel Levels

26th July 2015 Poison in your Washing Machine: Allergic Contact Dermatitis from Laundry Detergents, Softeners, Conditioners and Whiteners

17th October 2015: Health Risk: Vitamin and antioxidant supplements help cancer cells become malignant – latest research from Texas

31st May 2015: German Concern about Potentially Carcinogenic Aromatic Hydrocarbons in Cosmetics  

29th December 2012: Spreading diarrhea and vomit through the washing machine– The Norovirus propagator in our kitchen

and here are some fun reports…

21st June 2015: Bio-undies: Guilt free Passion with ‘Easy Emma’ and ‘Loose Harry’and Getting Rid of Garden Snails with Rent-a-Duck

4th March 2015: Hamburg Reeperbahn (St. Pauli): Germans install walls that urinate on passers-by

17th April 2014: Niche On-line Dating Services (Specialities: Herpes, Thrush and Genital Warts)

18th March 2014: Germany and Finland Joint Investigation: New Case of Sexual Cannibalism Including Self-mutilation (Castration) During Intercourse.

18th August 2012: How Bavarians and Austrians use their middle finger – Fingerhakeln: a men-only sport (did Arnold Schwarzenegger start training this way?).

You can also find some of my more humorous reports in the Alpine Press section of this site using the link here.